Antibiotic Misuse Fuels Deadly Resistance Crisis in Pakistan

- Pakistan - December 17, 2025
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The Growing Public Health Crisis of Antibiotic Resistance in Pakistan

In recent years, Pakistan has found itself grappling with a significant public health challenge: antimicrobial resistance (AMR). Medical professionals are sounding the alarm bells, stating that AMR is responsible for a staggering 200,000 to 300,000 deaths each year in the country. This issue isn’t just a statistic—it represents untold suffering for families and communities.

AMR occurs when bacteria, viruses, fungi, or parasites adapt and become resistant to medications. As a result, common infections that were once easily treatable are becoming alarmingly difficult, and sometimes impossible, to manage. The World Health Organization (WHO) points out that this evolution of pathogens is a global threat. It prolongs illnesses, escalates treatment costs, and sadly, raises the likelihood of complications and mortality.

Dr. Saeed Khan, a leading expert in the field, emphasizes that AMR is undermining modern medical practices. We’re at risk of facing dire consequences for surgeries and treatments like chemotherapy if we don’t take action. The situation is particularly precarious in Pakistan due to the overuse of antibiotics—often without prescriptions—and poor infection control in hospitals, among other factors.

Hospitals in Karachi report that common drug-resistant bacteria, such as Escherichia coli and Klebsiella pneumonia, are flourishing. These pathogens are serious players in urinary tract infections and other critical conditions, particularly in intensive care units (ICUs). Alarmingly, Dr. Khan mentions that bacterial pneumonia linked to influenza has become more deadly, as patients face delays in receiving effective treatment due to antibiotic ineffectiveness.

Children, the elderly, and immunocompromised individuals are particularly vulnerable to these drug-resistant infections. And while tuberculosis (TB) continues to plague the nation, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB has only added to the complexity of treatment. Patients suffering from these strains often require prolonged and costly care, with higher risks of treatment failure.

Studies indicate that between 40% and 70% of ICU patients in major hospitals are grappling with infections caused by multidrug-resistant organisms. This statistic underscores the urgent need for better practices in prescribing antibiotics and infection control.

As Dr. Syeda Sadaf Akbar points out, Pakistan ranks alarmingly low on the global scale of antibiotic resistance, sitting at 29th among 204 countries. The impact of AMR continues to rise each year, making this an unaddressed crisis that requires immediate attention.

What Can We Do?

Addressing this growing threat is a collective responsibility. Awareness is crucial—educating ourselves and others about the appropriate use of antibiotics can help slow down resistance rates. Furthermore, improving infection control practices in hospitals and advocating for rational antibiotic use can make a tangible difference.

If you’re interested in staying informed and connected with health initiatives targeting these pressing issues, consider exploring platforms like Pro21st. By engaging with such resources, we can empower ourselves and our communities to combat antibiotic resistance together. Remember, every informed choice matters!

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